Wolters Kluwer UpToDate Enterprise™: UpToDate® Lexidrug™: Facts and Comparisons® is a consolidated clinical and drug decision-support suite that delivers editor-reviewed clinical topics, drug monographs and interaction checking, and patient education via web, mobile, and EHR-integrated workflows, with enterprise analytics and optional AI-assisted search features.
Published May 16, 2026
Based on available community and institutional signals, churn drivers include:
| Starting Price | Enterprise: quote-based (not public). Individual signals: published individual-app subscription pricing available from the vendor | Enterprise: quote-based (not public) | Enterprise: quote-based (not public) |
| Primary suitability | Health systems seeking an integrated clinical and drug reference suite with editorial content and EHR embedding | Organizations prioritizing toxicology (Poisindex), drug pricing and supplier data (RED BOOK) | Organizations seeking concise, bullet-oriented clinical summaries and an alternative evidence-based CDS approach |
| Key Strengths | Combined clinical content and drug reference in a single vendor suite; broad clinical and pharmacy feature set; EHR integration options | Strong drug data ecosystem including toxicology and pricing modules | Concise, rapid-reference format preferred by some clinicians; vendor focus on curated content |
| Key Weaknesses | Mobile app performance and subscription management issues reported; enterprise licensing complexity | Differences in interaction coverage and functionality compared to other drug references have been reported by some users | Some users report adjustment challenges when switching from narrative-style references to bullet-format content |
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